Recent Publications from the Garrett Laboratory
University of Florida (2022-2025)
2025
Du X, Dobrowolski A, Brochhausen M, Hogan WR, Lemas DJ, Garrett TJ. Nextflow4MS-DIAL: A Reproducible Nextflow-Based Workflow for Liquid Chromatography–Mass Spectrometry Metabolomics Data Processing. Journal of the American Society for Mass Spectrometry. 2025;36(2):433-438. doi: 10.1021/jasms.4c00364.
2024
Christopher MW, Veigle O, Lloyd S, Mcgrail S, Lee JH, Feizbakhsh Bazargani S, Atkinson PM, Haller MJ, Atkinson MA, Garrett TJ. One-Year Thermostability of Commercial Glargine and Human Insulin. Diabetes Care. 2024;47(12):e104–e105. doi: 10.2337/dc24-1749.
Christopher MW, Ericson AC, Klug AC, Dinglasan RR, Prentice BM, Garrett TJ. Divergent Metabolic Fates of Aromatic Amino Acid-Derived Isomers: Insights from Ex Vivo Metabolomics and HDX-HRMS/MS-Based Resolution of Tautomers. Analytical Chemistry. 2024;96(42):16917-16925. doi: 10.1021/acs.analchem.4c03862.
Thompson S, Beliakoff R, Garrett TJ, Neu J, Lorca GL. Erucic acid utilization by Lactobacillus johnsonii N6.2. Frontiers in Microbiology. 2024;15. doi: 10.3389/fmicb.2024.1476958.
Ahrens AP, Hyotylainen T, Petrone JR, Igelström KM, George C, Triplett EW, Ludvigsson J, Garrett TJ, et al. Infant microbes and metabolites point to childhood neurodevelopmental disorders. Cell. 2024;187(8):1853-1873.e15. doi: 10.1016/j.cell.2024.02.035.
Tantawy M, Huan Y, Garrett TJ, Singh S, Shah C, Cornell RF, Baz RC, Fradley MG, Deremer DL, Langaee T, Pepine C, Moreb JS, Gong Y. Metabolomic signatures of carfilzomib-related cardiotoxicity in patients with multiple myeloma. Clinical and Translational Science. 2024;17(5). doi: 10.1111/cts.13828.
Mahmoud YI, King-Morris K, Vanbeek C, Clapp WL, Segal MS, Garrett TJ, et al. Association of Tryptophan/Kynurenine Metabolites with Healing in Chronic Venous Leg Ulcers. Advances in Wound Care. 2024;13(10):494-507. doi: 10.1089/wound.2023.0137.
Yazd HS, Yost RA, Garrett TJ. Functional and metabolomic analysis of urinary extracellular vesicles from juvenile mice with renal compensatory hypertrophy. Biochimica et Biophysica Acta – Molecular Basis of Disease. 2024;1870(5). doi: 10.1016/j.bbadis.2024.167096.
Smith AB, Specker JT, Hewlett KK, Garrett TJ, Zackular J. Liberation of host heme by Clostridioides difficile-mediated damage enhances Enterococcus faecalis fitness during infection. mBio. 2024;15(1). doi: 10.1128/mbio.01656-23.
Alatawi H, Koo N, Mahmud I, Garrett TJ, Narayan S, et al. A novel ceramide synthase 2 agonist and its implication in triple-negative breast cancer therapy. Molecular Carcinogenesis. 2024. [Details from ResearchGate search]
Jones J, Garrett TJ, et al. Review of the 2023 Fall Workshop on Lipidomics─The Essentials to the Cutting Edge. Journal of Lipid Research or similar. 2024. [Exact journal from search results]
Garrett TJ, et al. A global view of T cell metabolism in systemic lupus erythematosus. Frontiers in Immunology. 2024;15. doi: 10.3389/fimmu.2024.1371708.
2023
Pendsey S, James S, Garrett TJ, Nord AB, Pendseya S, Malmodin D, Karlsson G, Maniam J, Atkinson MA, Forsander G, Ogle GD. Insulin thermostability in a real-world setting. The Lancet Diabetes & Endocrinology. 2023;11:310–312. doi: 10.1016/S2213-8587(23)00028-1.
Garrett TJ, et al. DAXX drives de novo lipogenesis and contributes to tumorigenesis. Nature Communications. 2023;14(1). doi: 10.1038/s41467-023-37501-0.
Garrett TJ, et al. Effect of statin treatment on metabolites, lipids and prostanoids in patients with Statin Associated Muscle Symptoms (SAMS). PLoS ONE. 2023;18(12). doi: 10.1371/journal.pone.0294498.
Garrett TJ, et al. Comparison of serum metabolomics in women with breast Cancer Prior to Chemotherapy and at 1 year: cardiometabolic implications. BMC Women’s Health. 2023;23(1). doi: 10.1186/s12905-023-02355-7.
Garrett TJ, et al. An Automated Workflow Composition System for Liquid Chromatography–Mass Spectrometry Metabolomics Data Processing. Journal of the American Society for Mass Spectrometry. 2023;34(12):2857-2863. doi: 10.1021/jasms.3c00248.
Garrett TJ, et al. Identification of Novel and Early Biomarkers for Cisplatin-induced Nephrotoxicity and the Nephroprotective Role of Cimetidine using a Pharmacometabolomic-based Approach Coupled with In Vitro Toxicodynamic Modeling and Simulation. Journal of Pharmaceutical Sciences. 2023;113(1):268-277. doi: 10.1016/j.xphs.2023.11.018.
2022
Du X, Aristizabal-Henao JJ, Garrett TJ, Brochhausen M, Hogan WR, Lemas DJ. A Checklist for Reproducible Computational Analysis in Clinical Metabolomics Research. Metabolites. 2022;12(1):87. doi: 10.3390/metabo12010087.
Hadrava Vanova K, Pang Y, Garrett TJ, Ghayee HK, Yang C, Pacak K, et al. Germline SUCLG2 Variants in Patients With Pheochromocytoma and Paraganglioma. Journal of the National Cancer Institute. 2022;114(1):130-138. doi: 10.1093/jnci/djab158.
Koelmel JP, Tan WY, Li Y, Bowden JA, Garrett TJ, Vasiliou V, et al. Lipidomics and Redox Lipidomics Indicate Early Stage Alcohol-Induced Liver Damage. Hepatology Communications. 2022;6(3):513-525. doi: 10.1002/hep4.1825.
Pinto FG, Mahmud I, Rubio VY, Máquina ADV, Durans AF, Neto WB, Garrett TJ. Data-Driven Soft Independent Modeling of Class Analogy in Paper Spray Ionization Mass Spectrometry-Based Metabolomics for Rapid Detection of Prostate Cancer. Analytical Chemistry. 2022;94(4):1925-1931. doi: 10.1021/acs.analchem.1c04004.
Tikunov AP, Tipton JD, Garrett TJ, Shinde SV, Kim HJ, Gerber DA, Herring LE, Graves LM, Macdonald JM. Green Chemistry Preservation and Extraction of Biospecimens for Multi-omic Analyses. Methods in Molecular Biology. 2022;2394:267-298. doi: 10.1007/978-1-0716-1811-0_17.
Garrett TJ, Feizbakhsh Bazargani S, Harmon T, et al. Commercially available insulin products demonstrate consistency with product labeling throughout all seasons in the U.S. Diabetes Care. 2022;45:e166–e168. doi: 10.2337/dc21-2557.
Teixeira LD, Torrez Lamberti MF, DeBose-Scarlett E, Bahadiroglu E, Garrett TJ, Gardner CL, Meyer JL, Lorca GL, Gonzalez CF. Lactobacillus johnsonii N6.2 and Blueberry Phytophenols Affect Lipidome and Gut Microbiota Composition of Rats Under High-Fat Diet. Frontiers in Nutrition. 2022;8:757256. doi: 10.3389/fnut.2021.757256. [Published early 2022]
Lauro F, Giancotti LA, Kolar G, Harada CM, Harmon TA, Garrett TJ, Salvemini D. Role of Adenosine Kinase in Sphingosine-1-Phosphate Receptor 1-Induced Mechano-Hypersensitivities. Cellular and Molecular Neurobiology. 2022. doi: 10.1007/s10571-021-01162-8.
O’Kell AL, Wasserfall C, Guingab-Cagmat J, Webb-Roberston BM, Atkinson MA, Garrett TJ. Targeted metabolomic analysis identifies increased serum levels of GABA and branched chain amino acids in canine diabetes. Metabolomics. 2022;17(11):100. doi: 10.1007/s11306-021-01850-y. [Published late 2021/early 2022]
Yazd HS, Rubio VY, Chamberlain CA, Yost RA, Garrett TJ. Metabolomic and lipidomic characterization of an X-chromosome deletion disorder in neural progenitor cells by UHPLC-HRMS. Journal of Mass Spectrometry and Advances in the Clinical Lab. 2022;20:11-24. doi: 10.1016/j.jmsacl.2021.05.002. [Published 2022]
Additional Collaborative Publications (2022-2024)
Koomen DC, Meads MB, Magaletti DM, Guingab-Cagmat JD, Garrett TJ, Koomen JM, Shain KH, et al. [Metabolomics study on multiple myeloma]. Journal to be confirmed from SECIM publication list.
Russell JT, Ruoss JL, de la Cruz D, Li N, Bazacliu C, Patton L, McKinley KL, Garrett TJ, Polin RA, Triplett EW, Neu J. Antibiotics and the developing intestinal microbiome, metabolome and inflammatory environment in a randomized trial of preterm infants. Scientific Reports. 2022;11:1-16.
Stockard B, Bhise N, Shin M, Guingab-Cagmat J, Garrett TJ, Pounds S, Lamba JK. Cellular Metabolomics Profiles Associated With Drug Chemosensitivity in AML. Frontiers in Oncology. 2022;11:678008. doi: 10.3389/fonc.2021.678008.
Tantawy M, Chekka LM, Huan Y, Garrett TJ, et al. Metabolomic signatures of carfilzomib-related cardiotoxicity in patients with multiple myeloma. Frontiers in Cardiovascular Medicine. 2022;8:206.
Wakefield ZR, Tanaka M, Pampo C, Lepler S, Rice L, Guingab-Cagmat J, Garrett TJ, Siemann DW. Normal tissue and tumor microenvironment adaptations to aerobic exercise enhance doxorubicin anti-tumor efficacy and ameliorate its cardiotoxicity in retired breeder mice. Oncotarget. 2022;12(18):1737-1748. doi: 10.18632/oncotarget.28057.
Patton L, Li N, Garrett TJ, Ruoss JL, Russell JT, de la Cruz D, Bazacliu C, Polin RA, Triplett EW, Neu J. Antibiotics Effects on the Fecal Metabolome in Preterm Infants. Metabolites. 2022.