Casey A. Chamberlain
Casey A. Chamberlain graduated with his Ph.D. under the mentorship of Dr. Timothy J. Garrett in December 2019 from the University of Florida College of Medicine Biomedical Sciences Program. His graduate work was focused on the metabolomic characterization of the intestinal bacterial oxalobiome, a subset of the microbiome known to degrade bioavailable oxalate and offset the risk of calcium oxalate kidney stone disease. Prior to his graduate education, Casey earned his Bachelor of Science degree in chemistry from the University of Florida in 2013.
Casey is currently a Postdoctoral Research Associate in the laboratory of Dr. Gary J. Patti in the Department of Chemistry at Washington University in St. Louis (St. Louis, Missouri). His current research is focused on the biochemical connection between the intestinal microbiome and cancer metabolism.
Exposomics covers the interaction between environmental exposures, including from contaminants, diet, and drugs, with biological consequences. My specific interests within exposomics are to develop mass spectral and informatics approaches to more comprehensively characterize both the exposome (exogenous compounds) and endogenous (biological) molecules. I am also interested in the interaction between exogenous compounds and endogenous compounds which can lead to novel compounds, for example, DNA adducts, small molecule adducts, and oxidation products. As oxidation products are a nearly universal indication of biological stress, developing tools to improve the coverage of oxidized molecules will aid in numerous applications. Through my future research, I aim to develop techniques that more comprehensively covering molecules which are indicative of our exposures and biological response, allowing researchers to determine mechanisms and markers linking health and the environment. Currently I am working on PFAS software, lipidomics software, and workflows using personal exposure monitors to screen hundreds of thousands of chemical exposures. Ideally, the research and mentoring during my career will result in changes in policy and education, and the development of new treatments, which will reduce harmful exposures and their consequences.
Please go to http://innovativeomics.com/team/jeremy-p-koelmel-phd/ for access to my publication history, CV, and biosketch.