Vanessa Y. Rubio
Vanessa’s current research involves improving inefficiencies in global metabolomics workflows by reducing acquisition times using a combination or semi-targeted methodologies or developing automated processes for direct acquisition. Current work involves using these high-efficiency methods to perform biomarker detection on short stature populations distinct to isolated regions in Ecuador. Additional work includes research on tryptophan degradation impacted by the gut microbial composition.
Taylor A. Harmon
My research focus is on exploring new avenues for quantitative and semi-quantitative bioanalytical LC-MS. Current projects include development of clinical UHPLC-MS/HRMS methods for analysis of purines and antibiotics in biofluids, as well as novel microflow chromatography methodologies for global metabolomics. Benefits of microflow over conventional flow chromatography include reduced solvent consumption, lower sampling requirements, and higher ionization efficiency with mass spectrometric detection. Our goal is transfer existing laboratory procedures to the microflow régime for greener, safer, and more sensitive biomarker discovery.
Hoda Safari Yazd
Hoda Safari Yazd is a Ph.D. candidate in analytical chemistry at the University of Florida and working under the supervision of Prof. Richard Yost and Dr. Timothy Garrett. She received her B.Sc. in chemistry from Sharif University of Technology in 2015 and her M.Sc. in computational chemistry from the same school in 2017. Hoda’s research at UF primarily focuses on combining analytical chemistry tools and scientific programming for the metabolomic discovery of rare disorders. She is currently working on two projects; the first project concentrates on the detection of new biomarkers in meningiomas to improve early detection of this disease by employing machine learning as a tool on mass spectrometry-based metabolomics data. The second project is focused on the characterization of rare X-chromosome deletion disorders using metabolomics and lipidomics workflows by UHPLC-HRMS on neural progenitor cells.
Hamzeh Hassnein Ahmed
My ongoing research focuses on understanding the role of microbiota in cancer metabolism. I am currently interested in investigating the metabolism of colorectal cancer and how Fusobacterium spp. can alter the metabolism of colorectal cancer. In addition, part of my research is to study the metabolism of different Fusobacterium spp. My goal is to understand the metabolic liabilities in tumor progression by using the state of the art Ultra High-Pressure Liquid Chromatography coupled with High-Resolution Mass Spectrometry (UHPLC-HRMS)-based metabolomics. Hence, elucidating the metabolomic profile under the impact of Fusobacterium spp. in colorectal cancer cells can assist in developing a novel metabolic dependency that can enhance the development of suitable management strategies for colorectal cancer.
Sina Feizbakhsh Bazargani
I received my bachelor’s degree in chemistry from the Sharif University of Technology, which is the most prestigious university in Iran. To pursue my scientific life as an analytical chemist, I joined the University of Florida. I am currently a Ph.D. student under the supervision of Prof. Richard Yost and Dr. Timothy Garrett. My research now focuses on finding biomarkers in pancreatic tissue by using Mass Spectrometry MADLI and DESI Imaging. Simultaneously I am using the LC-MS method to compare the data to the Imaging method by employing statistical analysis. In the future, my focus is primary on implementing machine learning into the MS-MSI analysis.