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CD8 helps TCR catch slippery self pMHC

CD8 helps TCR catch slippery self pMHCCD8 helps TCR catch slippery self pMHC, Published online: 12 November 2018; doi:10.1038/s41590-018-0261-5A new model proposes that an applied force allows the...

A TCR mechanotransduction signaling loop induces negative selection in the thymus

A TCR mechanotransduction signaling loop induces negative selection in the thymusA TCR mechanotransduction signaling loop induces negative selection in the thymus, Published online: 12 November 2018;...

TCF-1 and HEB cooperate to establish the epigenetic and transcription profiles of CD4<sup>+</sup>CD8<sup>+</sup> thymocytes

TCF-1 and HEB cooperate to establish the epigenetic and transcription profiles of CD4+CD8+ thymocytesTCF-1 and HEB cooperate to establish the epigenetic and transcription profiles of...

Metabolic reprogramming of natural killer cells in obesity limits antitumor responses

Metabolic reprogramming of natural killer cells in obesity limits antitumor responsesMetabolic reprogramming of natural killer cells in obesity limits antitumor responses, Published online: 12...

TCF-1 takes HEB up a Notch

TCF-1 takes HEB up a NotchTCF-1 takes HEB up a Notch, Published online: 12 November 2018; doi:10.1038/s41590-018-0263-3Transcription factors orchestrate stage-specific gene expression during...