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IL-1β delivers a sweet deal

Interleukin 1β (IL-1β) is a cytokine associated with inflammation, obesity and metabolic dysregulation. Surprisingly, IL-1β is also required for maintaining steady-state glucose homeostasis by...

Innate B cells cleave to the marginal zone

The kinase Taok3 and protease ADAM10 mediate determination of the fate of marginal zone B cells.

Keeping skin inflammation local

Silencing of the chromatin remodeler Mi-2β in keratinocytes triggers local skin inflammation. Regulatory T cells activated by the cytokine TSLP control the shift from local skin inflammation to...