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Central tolerance: what you see is what you don't get!

Thymic selection shapes the repertoire of potentially autoreactive thymocytes that are allowed to mature. The expression pattern of self antigen seen by thymocytes determines the number and functional...

Decoding the immune response to successful influenza vaccination

Systems immunology identifies molecular and cellular signatures associated with adverse clinical events and antibody response to a vaccine against H1N1 influenza virus.

Multilayered ancestry of arterial macrophages

Arteries are colonized by macrophages of multiple origins, derived prenatally from the yolk sac and during an early postnatal wave from the bone marrow. During sepsis, blood monocyte-derived...