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Development of innate lymphoid cells

Innate lymphoid cells (ILCs) arise from distinct hematopoietic progenitors. Zook & Kee discuss the transcriptional programs that direct the development of natural killer cells and various ILC...

A versatile cell population

Innate lymphoid cells serve multiple roles in maintaining tissue homeostasis and responding to tissue insults and can contribute to chronic inflammatory diseases.

Family ties among CNS macrophages

Perivascular and subdural meningeal macrophages at the interface between the central nervous system and the periphery are self-renewing and arise from early embryonic precursors. Macrophages residing...

Bach2 is required for B cell and T cell memory differentiation

B cell and T cell memory differentiation requires the transcription factor Bach2, which inhibits the effector-cell fate by limiting antigen-receptor-stimulation-induced gene expression and restricting...