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Eosinophils and mast cells: a lineage apart

Single-cell transcriptome analysis has identified progenitor populations with mast-cell and eosinophil potential that are distinct from the neutrophil-monocyte lineage, segregate early in...

ILC2s masquerade as ILC1s to drive chronic disease

Tissue-resident innate lymphoid cells (ILCs) perform diverse roles in regulating mucosal homeostasis and inflammation. The transdifferentiation of ILC2s into interferon-γ (IFN-γ)-producing ILC1-like...