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Mass cytometry: blessed with the curse of dimensionality

Mass cytometry is shaping up to be a transformative technology for the description of immunological cell populations. In their Commentary, however, Newell and Cheng report that with great power comes...

Vive la peptide différence!

The thymic development of CD8+ T cells requires the presentation of different sets of peptides on major histocompatibility complex class I for positive selection and negative selection.